Interval Training with Different Intensities in
                    Overweight/Obese Adolescent Females

Wissal Abassi; Nejmeddine Ouerghi; Pantelis T. Nikolaidis; Lee Hill; Ghazi Racil; Beat Knechtle; Moncef Feki; Anissa Bouassida

doi:10.1055/a-1648-4653

International Journal of Sports Medicine, Table of Contents

Int J Sports Med 2022; 43(05): 434-443
DOI: 10.1055/a-1648-4653

Training & Testing

Interval Training with Different Intensities in Overweight/Obese Adolescent Females

Authors

Wissal Abassi

¹University of Jendouba, High Institute of Sport and Physical Education of Kef, UR13JS01, 7100 Kef, Tunisia

²University of Tunis El Manar, Faculty of Medicine of Tunis, Rabta Hospital, LR99ES11, 1007 Tunis, Tunisia

³Higher Institute of Sport and Physical Education of Ksar Said, University of “La Manouba”, Manouba 2010, Tunisia
Nejmeddine Ouerghi

¹University of Jendouba, High Institute of Sport and Physical Education of Kef, UR13JS01, 7100 Kef, Tunisia

²University of Tunis El Manar, Faculty of Medicine of Tunis, Rabta Hospital, LR99ES11, 1007 Tunis, Tunisia
Pantelis T. Nikolaidis

⁴School of Health and Caring Sciences, University of West Attica, Athens, Greece
Lee Hill

⁵Division of Gastroenterology and Nutrition, Department of Pediatrics, McMaster University, Hamilton, Canada
Ghazi Racil

³Higher Institute of Sport and Physical Education of Ksar Said, University of “La Manouba”, Manouba 2010, Tunisia
Beat Knechtle

⁶Medbase St. Gallen Am Vadianplatz, St. Gallen, Switzerland

⁷Institute of Primary Care, University of Zurich, Zurich, Switzerland
Moncef Feki

²University of Tunis El Manar, Faculty of Medicine of Tunis, Rabta Hospital, LR99ES11, 1007 Tunis, Tunisia
Anissa Bouassida

¹University of Jendouba, High Institute of Sport and Physical Education of Kef, UR13JS01, 7100 Kef, Tunisia

Abstract

To compare the effects of 12 weeks of high-intensity interval training (HIIT) versus moderate-intensity interval training (MIIT) on hematological and inflammatory markers in youth females, 38 overweight/obese females (16.4±1.0 yrs.) were randomly assigned to HIIT (2×6–8 repetitions of 30 s at 100–110% maximal aerobic speed (MAS), with 30 s active recovery between repetitions at 50% MAS; n=13), MIIT (2×6–8 repetitions of 30 s at 70–80% MAS, with 30 s active recovery between repetitions at 50% MAS; n=13), and a control group (CG, no intervention; n=12). Body composition, blood pressure, maximal heart rate, hematological and inflammatory markers (C-reactive protein [CRP], and erythrocyte sedimentation rate [ESR]) markers were assessed in all groups before and following the training program. Results revealed a significant (P<0.05) interaction effect for body composition, systolic blood pressure (SBP), MAS, maximal heart rate, and CRP. Within-group analyses for the HIIT and MIIT groups showed significant improvements in body mass (P=0.009 and P=0.025, respectively), BMI Z-score (P=0.011 and P=0.028, respectively), and MAS (P<0.001 and P=0.011, respectively). The HIIT program showed a significant decrease in body fat (P=0.002), waist circumference (P=0.002), maximal heart rate (P=0.003), SBP (P=0.001), and plasma CRP (P=0.004). In both groups, no signiﬁcant changes were observed in ESR and hematological markers after intervention. No variable changed in CG. HIIT was the effective method to manage cardiometabolic health and inflammatory disorders in obese youth.

Key words

cardiovascular fitness - C-reactive protein - interval training - obesity

Full Text

References

References
1 Kosti RI, Panagiotakos DB. The epidemic of obesity in children and adolescents in the world. Cent Eur J Public Health 2006; 14: 151-159
2 Di Cesare M, Bentham J, Stevens GA. et al. Trends in adult body mass index in 200 countries from 1975 to 2014: A pooled analysis of 1698 population-based measurement studies with 19·2 million participants. Lancet 2016; 387: 1377-1396
3 Oliveira TM, de Faria FR, de Faria ER. et al. Nutritional status, metabolic changes and white blood cells in adolescents. Rev Paul Pediatr 2014; 32: 351-359
4 Galic S, Oakhill JS, Steinberg GR. Adipose tissue as an endocrine organ. Mol Cell Endocrinol 2010; 316: 129-139
5 Keşkek ŞÖ, Kurşun Ö, Ortoğlu G. et al. Obesity without comorbidity may also lead to non-thyroidal illness syndrome. Adv Clin Exp Med 2018; 27: 1515-1520
6 Veronelli A, Laneri M, Ranieri R. et al. White blood cells in obesity and diabetes: effects of weight loss and normalization of glucose metabolism. Diabetes Care 2004; 27: 2051-2052
7 Zaldivar F, McMurray RG, Nemet D. et al. Body fat and circulating leukocytes in children. Int J Obes (Lond) 2006; 30: 906-911
8 Koh Y, Park KS. Responses of inflammatory cytokines following moderate intensity walking exercise in overweight or obese individual. J Exerc Rehabil 2017; 13: 472-476
9 Johannsen NM, Swift DL, Johnson WD. et al. Effect of different doses of aerobic exercise on total white blood cell (WBC) and WBC subfraction number in postmenopausal women: results from DREW. PloS One 2012; 7: e31319
10 Strasser B, Arvandi M, Siebert U. Resistance training, visceral obesity and inﬂammatory response: A review of the evidence. Obes Rev 2012; 13: 578-579
11 Chupel MU, Direito F, Furtado GE. et al. Strength training decreases inflammation and increases cognition and physical fitness in older women with cognitive impairment. Front Physiol 2017; 8: 377
12 Racil G, Ben Ounis O, Hammouda O. et al. Effects of high vs. moderate exercise intensity during interval training on lipids and adiponectin levels in obese young females. Eur J Appl Physiol 2013; 113: 2531-2540
13 Ouerghi N, Ben Fradj MK, Bezrati I. et al. Effects of high-intensity interval training on body composition, aerobic and anaerobic performance and plasma lipids in overweight/obese and normal-weight young men. Biol Sport 2017; 34: 385-392
14 Batacan RB, Duncan MJ, Dalbo VJ. et al. Effects of high-intensity interval training on cardiometabolic health: A systematic review and meta-analysis of intervention studies. Br J Sports Med 2017; 51: 494-503
15 Bartlett DB, Shepherd SO, Wilson OJ. et al. Neutrophil and monocyte bactericidal responses to 10 weeks of low-volume high-intensity interval or moderate-intensity continuous training in sedentary adults. Oxid Med Cell Longev 2017; 2017: 8148742
16 Robinson E, Durrer C, Simtchouk S. et al. Short-term high-intensity interval and moderate-intensity continuous training reduce leukocyte TLR4 in inactive adults at elevated risk of type 2 diabetes. J Appl Physiol (1985) 2015; 119: 508-516
17 Ouerghi N, Ben Fradj MK, Khammassi M. et al. Plasma chemerin in young untrained men: association with cardio-metabolic traits and physical performance, and response to intensive interval training. Neuro Endocrinol Lett 2017; 38: 59-66
18 Khammassi M, Ouerghi N, Said M. et al. Continuous moderate-intensity but not high-intensity interval training improves immune function biomarkers in healthy young men. J Strength Cond Res 2020; 34: 249-256
19 De Feo P. Is high-intensity exercise better than moderate-intensity exercise for weight loss?. Nutr Metab Cardiovasc Dis 2013; 23: 1037-1042
20 Racil G, Coquart JB, Elmontassar W. et al. Greater effects of high- compared with moderate-intensity interval training on cardio-metabolic variables, blood leptin concentration and ratings of perceived exertion in obese adolescent females. Biol Sport 2016; 33: 145-152
21 Harriss DJ, Macsween A, Atkinson G. Standards for ethics in sport and exercise science research: 2020 update. Int J Sports Med 2019; 40: 813-817
22 Abassi W, Ouerghi N, Ghouili H. et al. Greater effects of high- compared with moderate-intensity interval training on thyroid hormones in overweight/obese adolescent girls. Horm Mol Biol Clin Investig 2020; 41: 20200031
23 Neovius MG, Linné YM, Barkeling BS. et al. Sensitivity and specificity of classification systems for fatness in adolescents. Am J Clin Nutr 2004; 80: 597-603
24 Must A, Anderson SE. Body mass index in children and adolescents: considerations for population-based applications. Int J Obes 2006; 30: 590-594
25 World Health Organisation. Childhood Overweight and Obesity. WHO; 2017 Available from: https://www.who.int/dietphysicalactivity/child hood/en/
26 Rolland-Cachera MF, Cole TJ, Sempé M. et al. Body mass index variations: Centiles from birth to 87th year. Eur J Clin Nutr 1991; 45: 13-21
27 Tanner JM, Whitehouse RH. Clinical longitudinal standards for height, weight velocity and stages of puberty. Arch Dis Child 1976; 51: 170-179
28 Rey O, Rossi D, Nicol C. et al. Indirect assessment of aerobic capacity of obese adolescents: interest of a short intermittent, progressive and maximal running test. Sci Sports 2013; 28: e133-e139
29 Thivel D, O’malley G, Blourdier D. et al. Reproducibility of the intermittent Spartacus run test in obese adolescents. J Sports Med Phys Fitness 2017; 57: 1083-1088
30 Cohen J. Statistical Power Analysis for the Behavioral Sciences. 2nd ed. Hillsdale, NJ: Lawrence Erlbaum; 1988
31 Bekkelund SI, Jorde R. Lean body mass and creatine kinase are associated with reduced inflammation in obesity. Eur J Clin Invest 2017; 47: 803-811
32 Lin CC, Kardia SLR, Li CI. et al. The relationship of high sensitivity C-reactive protein to percent body fat mass, body mass index, waist-to-hip ratio, and waist circumference in a Taiwanese population. BMC Public Health 2010; 28: 579
33 Van Gaal LF, Mertens IL, De Block CE. Mechanisms linking obesity with cardiovascular disease. Nature 2006; 444: 875-880
34 Sandstad J, Stensvold D, Hoff M. et al. The effects of high intensity interval training in women with rheumatic disease: a pilot study. Eur J Appl Physiol 2015; 115: 2081-2089
35 Bartlett DB, Willis LH, Slentz CA. et al. Ten weeks of high-intensity interval walk training is associated with reduced disease activity and improved innate immune function in older adults with rheumatoid arthritis: a pilot study. Arthritis Res Ther 2018; 20: 127
36 Allen NG, Higham SM, Mendham AE. et al. The effect of high-intensity aerobic interval training on markers of systemic inflammation in sedentary populations. Eur J Appl Physiol 2017; 117: 1249-1256
37 Ingelsson E, Arnlov J, Sundstrom J. et al. Inflammation, as measured by the erythrocyte sedimentation rate, is an independent predictor for the development of heart failure. J Am Coll Cardiol 2005; 45: 1802-1806
38 Tenório TRS, Balagopal PB, Andersen LB. et al. Effect of low- versus high-intensity exercise training on biomarkers of inflammation and endothelial dysfunction in adolescents with obesity: A 6-month randomized exercise intervention study. Pediatr Exerc Sci 2018; 30: 96-105
39 Baeten D, Boots AM, Steenbakkers PG. et al. Human cartilage gp-39+,CD16+monocytes in peripheral blood and synovium: correlation with joint destruction in rheumatoid arthritis. Arthritis Rheum 2000; 43: 1233-1243
40 Reljic D, Frenk F, Herrmann HJ. et al. Effects of very low volume high intensity versus moderate intensity interval training in obese metabolic syndrome patients: a randomized controlled study. Sci Rep 2021; 11: 2836
41 National Institute for Health and Care Excellence (NICE). Weight management: lifestyle services for overweight or obese adults. Public Health Guideline PH53. London: NICE; 2014 Available from: www.nice.org.uk/guidance/ph53
42 Rossner S. Factors determining the long-term outcome of obesity treatment. In: Bjorntorp P, Brodoff BN (Eds.). Obesity. Philadelphia: J.B. Lippincott Co; 1991: 712-719
43 Jensen MD, Ryan DH, Donato KA. et al. Guidelines (2013) for managing overweight and obesity in adults. Obesity 2014; 22: S1-S410
44 Kunz P, Engel FA, Holmberg HC. et al. A meta-comparison of the effects of high-intensity interval training to those of small-sided games and other training protocols on parameters related to the physiology and performance of youth soccer players. Sports Med Open 2019; 5: 7
45 Gibala MJ, Jones AM. Physiological and performance adaptations to high-intensity interval training. Nestle Nutr Inst Workshop Ser 2013; 76: 51-60
46 Helgerud J, Hoydal K, Wang E. et al. Aerobic high-intensity intervals improve VO2max more than moderate training. Med Sci Sports Exerc 2007; 39: 665-671
47 Kiviniemi AM, Tulppo MP, Eskelinen JJ. et al. Cardiac autonomic function and high-intensity interval training in middle-age men. Med Sci Sports Exerc 2014; 46: 1960-1967
48 Ouerghi N, Ben Fradj MK, Bezrati I. et al. Effect of high-intensity interval training on plasma omentin-1 concentration in overweight/obese and normal-weight youth. Obes Facts 2017; 10: 323-331